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Call for Papers: Insights into Redox and Inflammatory Pathways in CNS Diseases

Introduction

Scientists have established through scientific research during the last ten years that oxidative stress and chronic inflammatory responses serve as primary mechanisms which lead to neuronal injury and synaptic dysfunction and progressive neurodegeneration. This Call for papers CNS diseases 2026 invites researchers, academicians, clinicians, and industry experts to contribute high-quality research which demonstrates how oxidative stress and neuroinflammation impact central nervous system disorders.

The disturbances in redox homeostasis together with the initiation of complex neuroinflammatory pathways directly impact both the development of diseases and their subsequent progression and treatment results. The special issue intends to establish a complete research platform which will enable scientists to study the various interrelated processes between molecular biology and neuropharmacology and clinical neuroscience and therapeutic development. The issue aims to foster interdisciplinary collaboration which will enhance our comprehension of CNS pathology while also discovering new therapeutic targets.

Scope

The special issue accepts original research articles and systematic reviews and short communications and methodological papers which study redox signaling in neurological disorders and related mechanisms. Researchers from various fields are invited to submit their work which includes basic science and translational research and clinical studies. The following subjects will be covered in this research study although the study will also consider other topics.

Researchers are encouraged to submit studies that:

  • Scientific understanding shows how oxidative stress affects the functioning of neurons and glial cells.
  • Researchers conduct complete studies about immune signaling and cellular responses in inflammatory pathways which operate within Central Nervous System disorders.
  • Researchers study how cells maintain redox balance through their antioxidant defense systems and their mechanisms for adapting to different conditions.
  • The Central Nervous System develops through mitochondrial function and reactive oxygen species (ROS) production and oxidative damage.
  • Researchers develop new experimental methods and computational models to investigate brain redox processes.
  • All therapeutic methods which aim to treat oxidative stress and neuroinflammation include both pharmacological and non-pharmacological approaches.
  • Researchers use redox and inflammatory processes to discover biomarkers which help develop diagnostic methods.
  • The research connects lab discoveries to clinical usage and patient outcomes through its translational studies.

    • Know More About This Issue

    Oxidative stress and neuroinflammation serve as primary characteristics which define multiple inflammatory pathways in CNS disorders that include epilepsy and Alzheimer’s disease and Parkinson’s disease and multiple sclerosis and traumatic brain injury. The conditions display two distinct features which include broken cellular equilibrium and high levels of reactive oxygen species and continuous activation of inflammatory signal transmission networks.

    Neuronal death and synaptic plasticity difficulties and disease advancement result from how redox imbalance interacts with immune system activity. The development of precise treatments which can delay or stop neurodegeneration requires knowledge about these relationships.

    This special issue aims to integrate insights from molecular, cellular, and clinical research to provide a holistic understanding of CNS diseases. The issue combines different research perspectives to accelerate the discovery of new therapeutic strategies which are based on scientific mechanisms and to enhance patient outcomes.

    redox signaling in neurological disorders

    Key Themes

    The submission process requires candidates to submit their work, which may address the following research areas.

  • Molecular and cellular mechanisms of oxidative stress in CNS diseases
  • The neuroinflammatory pathways which govern neurological diseases exert their effects through processes of regulation and impact.
  • The research progress in redox signaling has advanced our understanding of neurological disorders and their effects on cellular communication.
  • The three elements which contribute to CNS disorders are glial cells and immune responses and inflammatory pathways.
  • Neuroprotective strategies with antioxidant therapies and redox-based interventions
  • The study presents three emerging biomarkers together with diagnostic tools and imaging techniques
  • The field of CNS research has developed new experimental models and advanced technological capabilities.
  • The translational approaches create a connection between laboratory research findings and their application in clinical settings.

    • How We Support Your Submission

    The first service provides help with improving manuscript structure and manuscript clarity and academic writing standards.

  • The second service provides research design guidance together with methodology selection assistance and analytical method guidance.
  • The third service provides help with displaying difficult neuropharmacological and biological research results to audiences.
  • The process of document submission requires authors to follow journal specifications for formatting and referencing and submission procedures.
  • The service provides authors with constructive feedback and revision assistance which they can use to address peer-review comments.
  • The system simplifies document submission and review procedures which helps authors achieve their publication deadlines.

    • Journal Guidelines:

  • Manuscripts must be original, unpublished, and not under consideration by any other journal
  • Submissions must show researchers’ goals together with their research methods and their findings’ importance to science
  • Authors must adhere to the journal’s official Guide for Authors for formatting structure and citation style
  • All sources must be properly cited and manuscripts must meet academic integrity requirements together with anti-plagiarism standards
  • Authors must reveal all their funding sources together with their conflicts of interest and ethical approvals
  • Manuscripts need to be submitted through the Editorial Manager system under the category of “VSI: Redox and Neuroinflammation in CNS”
  • The peer-review process will assess all submissions to verify their originality and quality and their relevance to the field of study.

    • Important Dates

    Submission Deadline: 31 March 2027

    To ensure successful and timely submission to the special issue “Insights into Redox and neuroinflammation pathways in CNS Diseases,” researchers are encouraged to seek expert publication support from conceptualisation to final submission.

    Free Guide: How to Write the Journal Manuscript

    Book a free consultation to get guidance from the PhD assistance research lab for writing a credible research manuscript and submitting it to a high-quality journal.

    Reference

    JouElsevier. (2026, March 26). Insights into redox and inflammatory pathways in CNS diseases (Call for papers). Neuropharmacology. https://www.sciencedirect.com/journal/neuropharmacology

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